Premium
Recent Progress in Gas Phase Cucurbit[n]uril Chemistry
Author(s) -
Shen Jiewen,
Dearden David V.
Publication year - 2018
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201700095
Subject(s) - chemistry , gas phase , counterion , mass spectrometry , phase (matter) , nanotechnology , biochemical engineering , computational chemistry , organic chemistry , ion , chromatography , materials science , engineering
Abstract Cucurbit[n]urils (CB[n]s) are of great significance due to their unique molecular recognition properties and their potential applications in areas such as drug delivery or analytical assays. Gas phase studies, without interference from solvents or counterions, provide fundamental insights into the mechanism of CB[n] complex formation and binding. In this paper, we review the progress in gas phase CB[n] chemistry, mainly based on mass spectrometry, since 2011, including important discoveries in structural studies, mechanistic studies, and gas phase studies related to analytical or clinical applications of CB[n]s. We expect the use of gas phase methods to continue to expand and diversify.