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Potential Applications of Cucurbit[ n ]urils Inclusion Complexes in Photodynamic Therapy
Author(s) -
RobinsonDuggon José,
PérezMora Francisco,
DibonaVillanueva Luciano,
Fuentealba Denis
Publication year - 2018
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201700093
Subject(s) - photodynamic therapy , chemistry , inclusion (mineral) , drug delivery , cancer therapy , drug , toxicity , nanotechnology , combinatorial chemistry , pharmacology , cancer , medicine , organic chemistry , mineralogy , materials science
Cucurbit[ n ]urils (CB[ n ]s) have emerged as potential candidates for drug delivery in several areas due to their strong binding interactions and low toxicity. More recently, their benefits for a type of cancer treatment termed Photodynamic Therapy (PDT) have been recognized. The outcomes of this therapy rely on better drug delivery strategies and improving overall photoactivity of the drugs, which is where CB[ n ]s could have a strong impact. The effects of these molecular containers on photoactivity are discussed and new interesting work is highlighted.