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Iron and Single Electron Transfer: All is in the Ligand
Author(s) -
DesageEl Murr Marine,
Fensterbank Louis,
Ollivier Cyril
Publication year - 2017
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201700061
Subject(s) - halogenation , chemistry , reactivity (psychology) , iodide , bromide , ligand (biochemistry) , electron transfer , redox , combinatorial chemistry , catalysis , photochemistry , inorganic chemistry , organic chemistry , receptor , medicine , biochemistry , alternative medicine , pathology
This account describes some advances we have made in the field of iron catalysis. Two types of reactivity have been uncovered. Based on the use of an iron(II) precatalyst in the presence of NaBH 4 , the first one consists in a SET which can be useful for the reductive dehalogenation of iodide and bromide derivatives. Switching to the non‐innocent bis‐iminopyridine ligands promotes a previously undescribed Csp 2 −H activation reaction leading to biaryl derivatives. First clues into the intricate nature of the mechanism were obtained and suggested that the redox‐active bis‐iminopyridine ligand acts as an electron reservoir. The resulting buildup of electron density triggers the C−H bond breaking. All these findings are discussed in light of the existing literature and perspectives are given.