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Synthetic Applications of Aroyl‐ and Nitro‐substituted 2‐Aryl‐Cyclopropane‐1,1‐Dicarboxylates
Author(s) -
Selvi Thangavel,
Srinivasan Kannupal
Publication year - 2016
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201500093
Subject(s) - chemistry , cyclopropane , nitro , reactivity (psychology) , aryl , lewis acids and bases , organic chemistry , stereochemistry , medicinal chemistry , combinatorial chemistry , computational chemistry , catalysis , ring (chemistry) , medicine , alkyl , alternative medicine , pathology
Abstract The synthetic applications of aroyl‐ and nitro‐substituted D‐A cyclopropanes probed in the authors’ laboratory are reviewed. These cyclopropanes, though looking similar, exhibit markedly different reactivity patterns. Lewis acid‐mediated transformations of these cyclopropanes (in the presence or absence of a reaction partner) afford a variety of carbocycles and heterocycles. Mechanistic aspects of the reactions are discussed for clear understanding of the transformations.