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Cover Picture: Nanopore‐Based Analysis of Chemically Modified DNA and Nucleic Acid Drug Targets (Isr. J. Chem. 6‐7/2013)
Author(s) -
Larkin Joseph,
Carson Spencer,
Stoloff Daniel H.,
Wanunu Meni
Publication year - 2013
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201390006
Subject(s) - nanopore , chemistry , cover (algebra) , nucleic acid , dna , ionic bonding , solid state , molecule , nanotechnology , combinatorial chemistry , biophysics , biochemistry , organic chemistry , ion , materials science , mechanical engineering , engineering , biology
The cover picture shows a DNA molecule that is electrophoretically threaded, single‐file, through an ultrathin solid‐state nanopore. The DNA may contain methylated and hydroxymethylated cytosines, which can be distinguished by recording the ionic current through the nanopore during the transport of the molecule. A full description is provided in the Review by M. Wanunu et al. on p. 431 ff . Cover picture designed by Dr. Robert Johnson.