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The Development of Visible‐Light Photoredox Catalysis in Flow
Author(s) -
Garlets Zachary J.,
Nguyen John D.,
Stephenson Corey R. J.
Publication year - 2014
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201300136
Subject(s) - photoredox catalysis , chemistry , flow chemistry , visible spectrum , reagent , microreactor , flow (mathematics) , photochemistry , catalysis , nanotechnology , photocatalysis , organic chemistry , optoelectronics , mechanics , physics , materials science
Visible‐light photoredox catalysis has recently emerged as a viable alternative for radical reactions otherwise carried out with tin and boron reagents. It has been recognized that by merging photoredox catalysis with flow chemistry, slow reaction times, lower yields, and safety concerns may be obviated. While flow reactors have been successfully applied to reactions carried out with UV light, only recent developments have demonstrated the same potential of flow reactors for the improvement of visible‐light‐mediated reactions. This review examines the initial and continuing development of visible‐light‐mediated photoredox flow chemistry by exemplifying the benefits of flow chemistry compared with conventional batch techniques.