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Is Measuring OH . Radical Scavenging a Reasonable Measurement of Antioxidant Properties?
Author(s) -
Meyerstein Dan
Publication year - 2014
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201300123
Subject(s) - chemistry , radical , antioxidant , scavenging , in vivo , hydroxyl radical , photochemistry , organic chemistry , microbiology and biotechnology , biology
The measurement of the hydroxyl radical scavenging properties of a compound is not indicative on its antioxidant properties in vivo. To get such information one has to elucidate the mechanism of its reaction with typical secondary radicals, mainly typical RO 2 . radicals and to some degree with R . radicals. Elucidation of the mechanisms of reaction is essential before a conclusion regarding the antioxidant properties can be derived. One should remember that in vivo even vitamins C and E might act as pro‐oxidants.