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An Overview of Synergistic Data Tools for Biological Scrutiny
Author(s) -
Olender Tsviya,
Safran Marilyn,
Edgar Ron,
Stelzer Gil,
Nativ Noam,
Rosen Naomi,
Shtrichman Ronit,
Mazor Yaron,
West Michael D.,
Keydar Ifat,
Rappaport Noa,
Belinky Frida,
Warshawsky David,
Lancet Doron
Publication year - 2013
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.201200094
Subject(s) - compendium , computational biology , biobank , scrutiny , human disease , human genome , population , gene , biology , genetics , genome , medicine , political science , law , history , environmental health , archaeology
A network of biological databases is reviewed, supplying a framework for studies of human genes and the association of their genomic variations with human phenotypes. The network is composed of GeneCards, the human gene compendium, which provides comprehensive information on all known and predicted human genes, along with its suite members GeneDecks and GeneLoc. Two databases are shown that address genes and variations focusing on olfactory reception (HORDE) and transduction (GOSdb). In the realm of disease scrutiny, we portray MalaCards, a novel comprehensive database of human diseases and their annotations. Also shown is GeneKid, a tool aimed at generating novel kidney disease biomarkers using systems biology, as well as Xome, a database for whole‐exome next‐generation DNA sequences for human diseases in the Israeli population. Finally, we show LifeMap Discovery, a database of embryonic development, stem cell research and regenerative medicine, which links to both GeneCards and MalaCards.