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Lewis Acid Mediated Peterson Fluoroolefination
Author(s) -
Welch John T.,
Gregor Tamas,
Kornilov Andrei
Publication year - 1999
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.199900023
Subject(s) - chemistry , titanium tetrachloride , stereoselectivity , acetal , aryl , alkyl , lewis acids and bases , titanium , chloride , organic chemistry , medicinal chemistry , tetrachloride , catalysis , tin
Peterson olefination of the alkyl and aryl aldehydes with C,O ‐bis(triethylsilyl)fluoroketene acetal 1 promoted by titanium tetrachloride and dimethylaluminum chloride was investigated. Desired fluoroolefins were formed with high stereoselectivity and moderate to high yields.