Premium
Recent Developments in the Synthesis of Annonaceous Acetogenins
Author(s) -
Marshall James A.,
Hinkle Kevin W.,
Hagedorn Chad E.
Publication year - 1997
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.199700012
Subject(s) - chemistry , stereocenter , acetogenin , stereochemistry , organic chemistry , enantioselective synthesis , traditional medicine , annonaceae , catalysis , medicine
Synthetic routes to various bis‐THF annonaceous acetogenins and prototypes thereof are reviewed. These C 35 –C 37 long‐chain diethers exhibit a remarkable range of biological activities. The core unit, with six oxygenated stereogenic centers, provides a challenging target for asymmetric synthesis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom