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Homonuclear Magnetization Transfer Experiments Using Isotropic and Nonisotropic Mixing Schemes
Author(s) -
Bax Ad
Publication year - 1988
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.198800042
Subject(s) - homonuclear molecule , chemistry , heteronuclear molecule , isotropy , magnetization , coherence (philosophical gambling strategy) , decoupling (probability) , mixing (physics) , polarization (electrochemistry) , nuclear magnetic resonance , quantum mechanics , molecule , physics , magnetic field , organic chemistry , control engineering , engineering
The principles of homonuclear magnetization transfer via isotropic and non‐isotropic mixing schemes are discussed. Practical aspects of such experiments concern the minimization of the generation of multiple quantum coherence, minimization of rf power requirements, suppression of NOEs during mixing and minimization of relaxation losses. The analogy between these experiments and heteronuclear decoupling is briefly discussed. The efficiencies of several mixing schemes are compared and it is demonstrated experimentally that the resolution and sensitivity of the homonuclear cross polarization methods can be superior to the conventional COSY experiment.