Premium
On the Relation Between Reactivity and Selectivity
Author(s) -
Levine R.D.
Publication year - 1985
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.198500114
Subject(s) - chemistry , selectivity , reactivity (psychology) , inverse , index (typography) , constant (computer programming) , organic chemistry , catalysis , mathematics , geometry , medicine , alternative medicine , pathology , world wide web , computer science , programming language
Can one relate in a systematic fashion changes in the nature of the reactants to changes in the magnitude of the reaction rate constant? It is suggested that such correlations can be given a precise meaning and that the inverse correlation high selectivity—low reactivity is indeed valid. What need not always be true is that a single selectivity index (e.g., location of the transition state) suffices to quantitatively describe the correlation. When a single selectivity index does suffice we prove the reactivity—selectivity principle including the Hammond postulate.