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Cyclophilic Reactions of Allene‐1,3‐dicarboxylic Esters. Part 4. Pyrazolone Formation and a Novel Indole Synthesis from the Nucleophilic Addition of 1,2‐Diphenylhydrazine to Dimethyl Allene‐1,3‐dicarboxylate
Author(s) -
Onwuyali E. Ify,
Scheinmann Feodor
Publication year - 1985
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.198500088
Subject(s) - allene , chemistry , pyrazolone , indole test , pyrazolones , nucleophile , medicinal chemistry , organic chemistry , catalysis
Experiments are described for the addition of 1,2‐diphenylhydrazine to dimethyl allene‐1,3‐dicarboxylate and the subsequent conversion of dimethyl 3‐(1,2‐diphenylhydrazino)pent‐2‐enedioate (3) to either the pyrazolone (4) or a mixture of the indole (5) and the pyrazolone (4).