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Is the Effective Size of an Alkyl Group a Gauge of Dynamic Gearing?
Author(s) -
Hounshell W. Douglas,
Iroff Linda D.,
Iverson D. J.,
Wroczynski R. J.,
Mislow Kurt
Publication year - 1980
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.198000054
Subject(s) - chemistry , alkyl , steric effects , group (periodic table) , reduction (mathematics) , atom (system on chip) , similarity (geometry) , stereochemistry , organic chemistry , geometry , mathematics , artificial intelligence , computer science , image (mathematics) , embedded system
This paper presents a critical discussion of the perceived similarity between alkyl groups and mechanical gears. Specifically, we examine the notion that the availability of “free spaces” between the ligands of the central atom in an alkyl group leads to a reduction in the steric requirements of the group and, hence, to an effect on the rate of conformational interconversion. It is concluded that there is no compelling experimental evidence to support the operation of this type of dynamic gear effect.