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The Tetragonal Crystal Structure of 2:3 Deoxycholic Acid–Water Complex
Author(s) -
Tang C. P.,
PopovitzBiro R.,
Lahav M.,
Leiserowitz L.
Publication year - 1979
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197900059
Subject(s) - chemistry , deoxycholic acid , orthorhombic crystal system , hydrogen bond , tetragonal crystal system , molecule , crystallography , crystal structure , inclusion compound , bile acid , organic chemistry , biochemistry
The deoxycholic acid (DCA)–water (2:3) complex crystallises in space group P 4 1 2 1 2. The DCA molecules form hydrogen‐bonded layers which contain channels filled by chains of water molecules. These water molecules are linked by hydrogen bonds with each other and with the DCA molecules on the channel walls. The channel walls are thus hydrophilic unlike the hydrophobic channel walls found in the commonly observed orthorhombic P 2 1 2 1 2 1 inclusion complexes of DCA.