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Field Ionization Mass Spectrometry. II. FD Spectra of Nucleotides — Analysis of Methylation Products of Dinucleoside Phosphates
Author(s) -
Linscheid M.,
Feistner G.,
Budzikiewicz H.
Publication year - 1978
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197800026
Subject(s) - chemistry , methylation , fragmentation (computing) , nucleotide , mass spectrometry , nucleoside , mass spectrum , field desorption , ionization , analytical chemistry (journal) , chromatography , stereochemistry , organic chemistry , biochemistry , dna , ion , computer science , gene , operating system
The analysis of reaction products in methylation of four dinucleoside monophosphates (ApA, UpU, ApU, UpA) by FDMS is reported. Both the relative amounts of the various methylation products and the sites of methylation could be determined, the latter from the fragmentation patterns. The results are explained by the different reaction rates of the nucleoside moieties.