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1‐Phenylcycloalkylamine Derivatives. III
Author(s) -
Kalir A.,
Sadeh Shoshana,
Karoly Hava,
Shirin E.,
Balderman D.,
Edery H.,
Porath Gila
Publication year - 1975
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197500017
Subject(s) - chemistry , ritter reaction , trifluoroacetic acid , phencyclidine , yield (engineering) , solvent , organic chemistry , computational chemistry , biochemistry , catalysis , thermodynamics , receptor , physics , nmda receptor
A series of phencyclidine analogs has been prepared and subjected to pharmacological screening. None of them surpassed the activity of phencyclidine. It was found that trifluoroacetic acid as a solvent favorably influenced the yield of the Ritter reaction.