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A New X‐Ray Method for the Determination of the Quaternary Structure of Protein Complexes
Author(s) -
Hoppe W.
Publication year - 1972
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197200036
Subject(s) - chemistry , protein quaternary structure , protein subunit , crystallography , quaternary , labelling , x ray , biochemistry , optics , paleontology , physics , biology , gene
The determination of the spatial arrangement of subunits in protein complexes is possible by an application of a new method. After appropriate labelling of the subunits with heavy atoms the distances between the subunits can be found from X‐ray experiments. Theoretical and experimental considerations allow us to deduce these distances and to find the relative positions of the subunits within the protein complex.