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Bromination of p‐Bromophenol in the Presence of Pyridine
Author(s) -
Somaskandan K.,
Sridhar N.,
Rajaram J.,
Kuriacose J.C.
Publication year - 1971
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197100078
Subject(s) - chemistry , halogenation , pyridine , reaction rate constant , medicinal chemistry , bromophenol blue , limiting , stereochemistry , kinetics , organic chemistry , chromatography , mechanical engineering , engineering , physics , quantum mechanics
The role of pyridine (Py) in the bromination of p‐bromophenol (ArH) in CCl 4 has been investigated. At constant concentrations of ArH and Br 2 , the rate of disappearance of Br 2 increases to reach a limiting value as the concentration of Py is increased. The mechanism suggested to account for the rate expression, Rate = constant [ArH] [Br 2 ] T [Py] T , obtained from the initial rate studies, involves the interaction between ArH and the brominating species Py. Br 2 , in the rate determining step. Py acts as a catalyst probably by virtue of its ability to polarise the Br‐Br bond.