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Base Induced Isomerization of γ, δ‐Epoxyketones
Author(s) -
Gaoni Y.
Publication year - 1971
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197100010
Subject(s) - chemistry , cyclopropane , isomerization , hexane , base (topology) , stereochemistry , medicinal chemistry , organic chemistry , catalysis , ring (chemistry) , mathematical analysis , mathematics
Base treatment of open‐chain γ, δ ‐ epoxyketones yields usually two cyclopropane derivatives, a trans‐1‐acy1‐2(α ‐ hydroxyalkyl) cyclopropane (II) and a 2‐hydroxy‐3‐oxabicyclo[3, 1, 0] hexane (III). The NMR spectra and some other physical properties of compounds II and III and of some of their transformation products are reported.