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The Direct Synthesis of β‐hydroxy‐acids by Lithium Naphthalene and Acetic Acid
Author(s) -
Watanabe S.,
Suga K.,
Fujita T.,
Fujiyoshi K.
Publication year - 1970
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.197000088
Subject(s) - chemistry , naphthalene , acetic acid , lithium (medication) , organic chemistry , medicine , endocrinology
Lithium naphthalene reacts with acetic acid to give α‐anion of lithium acetate. The reaction of this anion with various ketones gives the corresponding β‐hydroxy‐acids in good yield.