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Nitrofuryl Pyrazoles and Nitrofuryl Isoxazoles
Author(s) -
Haber R. G.,
Schoenberger E.
Publication year - 1968
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.196800080
Subject(s) - chemistry , nitration , hydroxylamine , hydrazine (antidepressant) , ring (chemistry) , furan , pyrazole , medicinal chemistry , organic chemistry , chromatography
The synthesis of a number of antibacterial 3,5‐disubstituted pyrazoles and isoxazoles starting from beta‐diketones and a hydrazine or hydroxylamine respectively is described. A furyl or 5‐nitrofuryl group was always one of the substituents. The nitration of the furan ring could be performed at any stage.