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Extension of the Rate Equations for Enzyme Inhibition
Author(s) -
Kremer M. L.
Publication year - 1967
Publication title -
israel journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.908
H-Index - 54
eISSN - 1869-5868
pISSN - 0021-2148
DOI - 10.1002/ijch.196700027
Subject(s) - chemistry , uncompetitive inhibitor , non competitive inhibition , enzyme , rate equation , enzyme inhibition , extension (predicate logic) , simultaneous equations , simultaneous equations model , thermodynamics , biochemistry , kinetics , econometrics , mathematical analysis , economics , differential equation , classical mechanics , physics , computer science , programming language , mathematics
Rate equations for competitive, uncompetitive and noncompetitive enzyme inhibition at low inhibitor concentration are derived. The possibility of distinguishing between these mechanisms is discussed. The relation of these equations to other rate equations and the determination of the total enzyme concentration from inhibition studies are discussed.