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New perspectives on screening and early detection of endometrial cancer
Author(s) -
Costas Laura,
FriasGomez Jon,
Guardiola Magdalena,
Benavente Yolanda,
Pineda Marta,
Pavón Miquel Á.,
Martínez José M.,
Climent Maite,
Barahona Marc,
Canet Júlia,
Paytubi Sonia,
Salinas Mónica,
Palomero Luis,
Bianchi Ilaria,
Reventós Jaume,
Capellà Gabriel,
Diaz Mireia,
Vidal August,
Piulats Josep M.,
Aytés Álvaro,
Ponce Jordi,
Brunet Joan,
Bosch Francesc X.,
MatiasGuiu Xavier,
Alemany Laia,
Sanjosé Silvia
Publication year - 2019
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.32514
Subject(s) - endometrial cancer , female circumcision , medicine , sampling (signal processing) , cervix , gynecology , cancer , perspective (graphical) , genital tract , computer science , physiology , artificial intelligence , filter (signal processing) , computer vision
Due to the anatomical continuity of the uterine cavity with the cervix, genomic exploitation of material from routine Pap smears and other noninvasive sampling methods represent a unique opportunity to detect signs of disease using biological material shed from the upper genital tract. Recent research findings offer a promising perspective in the detection of endometrial cancer, but certain questions need to be addressed in order to accelerate the implementation of novel technologies in a routine screening or clinical setting. We discuss here new perspectives on detection of endometrial cancer using genomic and other biomarkers in minimally invasive sampling methods with a special focus on public health classic screening criteria, highlighting current gaps in knowledge.