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Retraction: Investigation of cross‐contamination among human cell lines used in China by Mingzhen Wang, Meimei Yang, Yuehong Liu, Yaqing Huang, Fang Ye, Congyi Zheng and Chao Shen
Author(s) -
Mingzhen Wang,
Meimei Yang,
Yuehong Liu,
Yaqing Huang,
Fang Ye,
Chengchao Zheng,
Chao Shen
Publication year - 2018
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.30923
Subject(s) - hela , cell culture , china , fang , cell , human cell , cancer cell lines , authentication (law) , medicine , biology , cancer research , cancer , genetics , cancer cell , computer science , computer security , history , zoology , archaeology
Increasing attention has been paid to the hazard of cell line cross-contamination. More journals are requiring that cell lines be authenticated prior to manuscript submission. China Center for Type Culture Collection (CCTCC) has authenticated cell lines for publications in the International Journal of Cancer since 2009. Between 2010 and 2016, we authenticated 485 cell lines from 66 Chinese universities and research institutes. Almost 50% of cell lines were misidentified, most were completely replaced by other cell lines (mainly HeLa and its sublines). The number of cell lines we received for authentication increased dramatically after 2013, but the proportion of misidentified cell lines remained elevated (over 50%). We strongly recommend that researchers take authentication of cell lines seriously and routinely perform authentication of the cell lines used in their laboratories. This article is protected by copyright. All rights reserved.