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Adherence to nutrition‐based cancer prevention guidelines and breast, prostate and colorectal cancer risk in the MCC ‐ S pain case–control study
Author(s) -
Romaguera Dora,
GraciaLavedan Esther,
Molinuevo Amaia,
de Batlle Jordi,
Mendez Michelle,
Moreno Victor,
Vidal Carmen,
Castelló Adela,
PérezGómez Beatriz,
Martín Vicente,
Molina Antonio J.,
DávilaBatista Verónica,
DierssenSotos Trinidad,
GómezAcebo Inés,
Llorca Javier,
Guevara Marcela,
Castilla Jesús,
Urtiaga Carmen,
LlorensIvorra Cristóbal,
FernándezTardón Guillermo,
Tardón Adonina,
Lorca José Andrés,
MarcosGragera Rafael,
Huerta José María,
OlmedoRequena Rocío,
JimenezMoleon José Juan,
Altzibar Jone,
de Sanjosé Silvia,
Pollán Marina,
Aragonés Núria,
CastañoVinyals Gemma,
Kogevinas Manolis,
Amiano Pilar
Publication year - 2017
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.30722
Subject(s) - medicine , prostate cancer , colorectal cancer , breast cancer , cancer , oncology , cancer prevention , logistic regression , confounding , case control study , population , gynecology , prostate , environmental health
Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition‐based guidelines for cancer prevention and prostate, breast and colorectal cancer, in the MCC‐Spain case–control study. A total of 1,718 colorectal, 1,343 breast and 864 prostate cancer cases and 3,431 population‐based controls recruited between 2007 and 2012, were included in the present study. The World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) score based on six recommendations for cancer prevention (on body fatness, physical activity, foods and drinks that promote weight gain, plant foods, animal foods and alcoholic drinks; score range 0–6) was constructed. We used unconditional logistic regression analysis adjusting for potential confounders. One‐point increment in the WCRF/AICR score was associated with 25% (95% CI 19–30%) lower risk of colorectal, and 15% (95% CI 7–22%) lower risk of breast cancer; no association with prostate cancer was detected, except for cases with a Gleason score ≥7 (poorly differentiated/undifferentiated tumours) (OR 0.87, 95% CI 0.76–0.99). These results add to the wealth of evidence indicating that a great proportion of common cancer cases could be avoided by adopting healthy lifestyle habits.