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Incidence and risk factors for childhood brain tumors in the ILE DE France
Author(s) -
Cordier Sylvaine,
Iglesias MariaJosé,
Le Goaster Corinne,
Guyot MarieMadeleine,
Mandereau Laurence,
Hemon Denis
Publication year - 1994
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910590612
Subject(s) - medicine , risk factor , incidence (geometry) , demography , odds ratio , case control study , logistic regression , population , breastfeeding , pediatrics , environmental health , physics , sociology , optics
A case‐control study investigating risk factors for childhood brain tumors was conducted in the lle de France (Paris region). During a 2‐year period (1985–1987) 109 newly diagnosed cases were identified and, of these, 75 could be interviewed. In the same region, 113 population controls, frequency‐matched for year of birth, were interviewed. Odds ratios adjusted for child's age and sex and for maternal age were estimated for each risk factor present in utero or during childhood by conditional logistic regression. Statistically significant associations were found for the following risk factors: farm residence, cat scratches, home treated with pesticides, passive smoking, family history of cancer, antihistamine intake. Intake of vitamin supplements during childhood was associated with a decrease in risk. This study is part of a multicentric case‐control study coordinated by the International Agency for Research on Cancer and its results will be compared for consistency, and pooled with those of other centers using the same protocol.