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Evaluation of circulating tumor necrosis factor‐α in patients with gynecological malignancies
Author(s) -
De Jaco Pierandrea,
Asselain Bernard,
Orlandi Camillo,
Fridman Wolf Herman,
Teillaud JeanLuc
Publication year - 1991
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910480311
Subject(s) - medicine , ovarian carcinoma , stage (stratigraphy) , tumor necrosis factor alpha , cervical carcinoma , carcinoma , epithelioma , pathology , gastroenterology , oncology , gynecology , ovarian cancer , cervical cancer , cancer , biology , paleontology
TNF‐α levels in sera from patients with gynecological cancers were evaluated by ELISA and compared with those of patients with benign ovarian cysts or of anonymous healthy donors. Patients with cervical and endometrial carcinoma and with benign ovarian cysts showed levels of TNF‐α similar to those of healthy donors. In contrast, significantly increased levels of TNF‐α were found in patients with ovarian carcinoma, regardless of the stage of disease.