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4. The role of the epidermal growth factor receptor and the c‐erbB‐2 protein in breast cancer
Author(s) -
Gullick W. J.
Publication year - 1990
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910460708
Subject(s) - breast cancer , epidermal growth factor , cancer cell , epidermal growth factor receptor , biology , cancer , cancer research , receptor , pathology , medicine
Breast cancer cells are derived from epithelial cells lining the ducts of the breast. One of the fundamental characteristics that distinguish tumour cells from normal cells is that cancer cells grow in an apparently unregulated way. Understanding the mechanisms that regulate the growth and differentiation of normal breast epithelial cells and the differences between these systems in cancer cells is one of the central goals of research into the cell biology of breast cancer.