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Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer
Author(s) -
Zaridze D. G.,
Chevchenko V. E.,
Levtshuk A. A.,
Lifanova Y. E.,
Maximovitch D. M.
Publication year - 1990
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910450502
Subject(s) - arachidonic acid , linoleic acid , oleic acid , breast cancer , stearic acid , palmitic acid , chemistry , membrane , fatty acid , medicine , unsaturated fatty acid , cancer , biochemistry , endocrinology , food science , organic chemistry , enzyme
Five fatty acids (FA) 2 saturated, palmitic (C16:0), stearic (C18:0) and 3 unsaturated, oleic (C18:1), linoleic (C18:2), arachidonic (C20:4) acids have been studied in the red cell membranes of breast cancer patients and controls. Statistically significant decrease in the risk of breast cancer has been found to be associated with increase in the levels of linoleic acid in pre‐menopausal women and of arachidonic acid in the post‐menopausal group.