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Seroepidemiologic survey for antibodies to human retroviruses in human and non‐human primates in Brazil
Author(s) -
AndradaSerpa Maria José,
Tosswill Jennifer,
Schor Doris,
Linhares Denise,
Dobbin Jane,
Pereira Marguerite S.
Publication year - 1989
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910440302
Subject(s) - lymphoma , medicine , incidence (geometry) , antibody , tropical spastic paraparesis , hematology , virology , cancer , retrovirus , anemia , amazon rainforest , immunology , virus , biology , physics , myelopathy , psychiatry , spinal cord , optics , ecology
The prevalence of antibodies to HTLV‐I and HIV‐I in Brazil was determined by testing sera from: (a) 119 members of an isolated Amazonian community of African origin; (b) 100 voluntary blood donors in Rio de Janeiro; (c) 215 patients treated at the Hematology Service, National Cancer Institute, Rio de Janeiro, and (d) 44 Cebus apella New World monkeys, wild‐caught in Amazonia. Anti‐HTLV‐I was detected in I (0.84%) of 119 Amazonians, in 8 (3.72%) of the 215 patients and in none of the blood donors or monkeys. The high prevalence found in patients included 4 (5.79%) of 69 with non‐Hodgkin lymphoma, 2 (5.88%) of 34 with Hodgkin lymphoma, I (16.66%) of 6 patients with diagnosis of anemia and I (20%) of 5 with HIV‐I infection. Anti‐HIV‐l was found in 7 (14.89%) of 47 patients and in none of the other groups. The high incidence of HTLV‐I infection in the patient group suggests that this retrovirus is endemic in parts of Brazil.