Premium
Periampullary, colorectal and gastric cancer in two siblings
Author(s) -
Schlossberg Daniel,
Weber Walter,
Stoffel Urs,
Henggeler Karl,
Stocker Hans,
Foeppl Mario,
Akovbiantz Arik
Publication year - 1988
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910420607
Subject(s) - medicine , colorectal cancer , gastroenterology , gastric carcinoma , carcinoma , familial adenomatous polyposis , cancer , oncology
We describe a sibship affected by subsequent periampullary, colorectal and gastric carcinoma. Three of 4 siblings (2 males, 1 female) developed a periampullary carcinoma at the age of 20, and the 2 brothers subsequently had colorectal and gastric carcinoma. One of them also had familial adenomatous polyposis. There is suggestive evidence of vertical transmission of a gene predisposing to a hereditary colorectal carcinoma syndrome.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom