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CA 125 in the monitoring of response to chemotherapy of ovarian carcinoma
Author(s) -
Quaranta M.,
Lorusso V.,
Coviello M.,
Micelli G.,
Casamassima A.
Publication year - 1988
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910410814
Subject(s) - chemotherapy , ovarian carcinoma , epithelial ovarian carcinoma , medicine , oncology , carcinoma , ovarian cancer , gastroenterology , cancer
CA 125 serum levels were assessed in 23 patients undergoing chemotherapy for advanced epithelial ovarian carcinoma (EOC). Rising, falling and unchanged levels correlated with disease in 21 out of 23 (95%) cases. Ten out of 11 patients who showed objective response to chemotherapy had a decrease in antigen levels. Two out of 3 patients with stable disease had unchanged values. Progression was always associated with rising levels. CA 125 is a reliable marker for monitoring response to chemotherapy in advanced epithelial ovarian carcinoma.