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Risk factors for cutaneous malignant melanoma in a northern italian population
Author(s) -
Cristofolini Mario,
Tasin Laura,
Zumiani Giuseppe,
Franceschi Silvia,
Talamini Renato,
Piscioli Francesco,
La Vecchia Carlo
Publication year - 1987
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910390205
Subject(s) - medicine , melanoma , sun exposure , dermatology , skin type , skin cancer , relative risk , family history , case control study , population , surgery , cancer , environmental health , confidence interval , cancer research
Abstract The relationship between cutaneous malignant melanoma (CMM) and the colour of skin, hair and eyes, the extent of sun exposure and reaction to it, education, and the occurrence of skin neoplasms in patients and their families was evaluated in a case‐control study of 103 cases of CMM and 205 control subjects hospitalized for acute conditions other than malignant or hormonal disease. A significantly higher risk was associated with fair skin as compared to dark/medium skin (RR = 4.0; 95% CI: 1.5‐10.5) and positive family history for CMM (RR = 8.1; 95% CI: 1.0‐200.9). CMM seemed to occur more frequently, but not significantly so, in individuals with brown or blond hair, higher education and clinically diagnosed dysplastic naevi. Outdoor occupation and heavy sun exposure in the last 20 years seemed to increase the risk of CMM in sunexposed sites but to be negatively associated with CMM in normally unexposed sites.