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Inhibitory action of ASPARAGUS racemosus on DMBA‐induced mammary carcinogenesis in rats
Author(s) -
Rao A. R.
Publication year - 1981
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910280512
Subject(s) - dmba , asparagus racemosus , carcinogenesis , mammary tumor , asparagus , medicine , endocrinology , biology , pharmacology , traditional medicine , cancer , botany , breast cancer , medicinal plants
The present paper reports the inhibitory effect of Asparagus racemosus on DMBA‐induced mammary tumorigenesis in rats of Holtzman strain. When virgin female rats, normal or primed with 17‐β‐estradiol treatment, are put on diets containing 0.25%, 0.5%, 1% or 2% Asparagus root extract powder prior to their exposure to DMBA, mammary tumor incidence shows a sharp decline.