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A note on the role of dietary retinol and carotene in human gastro‐intestinal cancer
Author(s) -
Modan B.,
Cuckle H.,
Lubin F.
Publication year - 1981
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910280405
Subject(s) - carotene , retinol , vitamin , cancer , carotenoid , food intake , carcinogenesis , medicine , physiology , food science , beta carotene , biology
Dietary data relating to 406 patients with gastrointestinal cancers (cases) and 812 controls have been analysed to test the hypotheses that dietary vitamin A (retinol) and its precursor, carotene, may be protective agents in human carcinogenesis. There was no deficit among cases in the intake of retinol‐containing food items whereas several of the main carotene‐containing fruits and vegetables were eaten less often among cases than among controls. However, when total daily intake was estimated, there was no protective effect of carotene, perhaps implying that some other constituent of the fruits and vegetables is protective.