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Macrophage content and immunogenicity of C57BL/6J and BALB/cByJ methylcholanthrene‐induced sarcomas
Author(s) -
Evans Robert,
Lawler Ellen M.
Publication year - 1980
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910260618
Subject(s) - immunogenicity , methylcholanthrene , macrophage , immunology , biology , medicine , immune system , in vitro , carcinogen , biochemistry
A total of 33 methylcholanthrene‐induced sarcomas, growing in C57BL/6J or BALB/cByJ mice, were tested for their immunogenicity and for their relative mac‐rophage content. No relationship was demonstrated between these two characteristics. These results suggest that the direct correlation between macrophage content and immunogenicity demonstrated in rat tumor model systems may not hold for other systems.