Somatic cell hybrids producing antibodies specific to human fibronectin | Zendy

Zardi Luciano | Zendy; Carnemolla Barbara | Zendy; Siri Annalisa | Zendy; Santi Leonardo | Zendy; Accolla Roberto S. | Zendy

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Somatic cell hybrids producing antibodies specific to human fibronectin

Author(s) -

Zardi Luciano,

Carnemolla Barbara,

Siri Annalisa,

Santi Leonardo,

Accolla Roberto S.

Publication year - 1980

Publication title -

international journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.475

H-Index - 234

eISSN - 1097-0215

pISSN - 0020-7136

DOI - 10.1002/ijc.2910250304

Subject(s) - fibronectin , somatic cell , hypoxanthine guanine phosphoribosyltransferase , antibody , monoclonal antibody , biology , microbiology and biotechnology , hypoxanthine phosphoribosyltransferase , spleen , cell , immunology , biochemistry , gene , mutant

We have produced somatic cell hybrids between mouse plasmocytoma cells deficient in hypoxanthine phosphoribosyltransferase (P3 × 63 Ag8) and spleen cells derived from mice immunized with purified human plasma fibronectin. We report herein the properties of monoclonal anti‐fibronectin antibodies released by eight different clones.

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