Premium
Cervical carcinoma: Detection of herpes simplex virus RNA in cells undergoing neoplastic change
Author(s) -
McDougall James K.,
Galloway Denise A.,
Fenoglio Cecilia M.
Publication year - 1980
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910250102
Subject(s) - herpes simplex virus , rna , virus , pathology , cervical cancer , cervical carcinoma , dna , carcinoma , virology , biology , cancer research , medicine , cancer , gene , biochemistry , genetics
3 H‐HSV‐2 DNA has been hybridized in situ to frozen sectioned tissue from human cervical biopsies. RNA complementary to the virus‐specific probe was detected in cells undergoing pre‐malignant changes, but not in the cells of the fully developed squamous‐cell cancer.