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Transplanted cultured cells from pregnancy‐dependent mammary tumors have a heterogenous developmental potential
Author(s) -
Aidells Bruce D.,
Lee Audrey E.
Publication year - 1979
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910230520
Subject(s) - mammary gland , biology , pregnancy , fat pad , pathology , mammary tumor , endocrinology , medicine , adipose tissue , cancer , breast cancer , genetics
Cultured cells derived from pregnancy‐dependent mouse mammary tumors (plaques) when transplanted into the gland‐free mammary fat pad display a heterogeneous developmental potential. They not only gave rise to plaques but also produced normal mammary gland, hyperplastic alvoelar nodules (HAN), and autonomous mammary tumors.

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