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Abnormalites in evening plasma prolactin levels in nulliparous women with benign or malignant breast disease
Author(s) -
Tarquini A.,
di Martino L.,
Malloci A.,
Kwa H. G.,
van der Gugten A. A.,
Bulbrook R. D.,
Wang D. Y.
Publication year - 1978
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910220608
Subject(s) - prolactin , abnormality , medicine , etiology , breast disease , disease , population , physiology , mammary gland , gynecology , obstetrics , pregnancy , endocrinology , hormone , breast cancer , cancer , biology , environmental health , psychiatry , genetics
In the present study the assay results of prolactin concentrations in serial samples of blood obtained from premenopausal women with benign or malignant disease of the breast are compared with—and discussed in relation to—findings reported in earlier studies based on single samples of blood taken at various times from a large and ostensibly normal population of women. The finding of an abnormality in nycthemeral prolactin levels in the established disease is considered to strengthen the concept that the same abnormality found in high‐risk groups is of aetiological importance.