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Growth characteristics in vitro of hybrids between normal and transformed cell lines
Author(s) -
le Borgne de Kaouël C.,
Billard C.,
MacieiraCoelho A.
Publication year - 1978
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910210315
Subject(s) - hybrid , biology , cell division , in vitro , cell , cell culture , crowding , cell growth , microbiology and biotechnology , genetics , botany , neuroscience
Sensitivity to the inhibition of division during cell crowding in vitro was determined for hybrids between normal and tumor cell populations of human and mouse origin. Interspecies hybrids were more sensitive to cell crowding than intraspecies hybrids. The results suggest that the inhibition of cell division due to crowding was more dependent upon the species of origin rather than on the normal or transformed character of the parental cell lines of the hybrid cell populations.