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Primary tumor immunity in nude mice
Author(s) -
Prehn Liisa M.,
Outzen Henry C.
Publication year - 1977
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910190514
Subject(s) - immunity , immunology , medicine , cellular immunity , biology , pathology , immune system
Tumor implants grew better in radiated or in newborn nu/nu mice than in adult nu/nu controls when, and only when, the tumors were demonstrably immunogenic in normal mice. This result suggests primary immunity. No evidence of immunological memory was found by immunization‐challenge type experiments in the nude mice.