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Rate‐limiting step in the progression of mouse breast tumors
Author(s) -
Prehn Richmond T.
Publication year - 1977
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910190511
Subject(s) - limiting , breast cancer , medicine , cancer , oncology , incidence (geometry) , hormone , etiology , biology , pathology , cancer research , mechanical engineering , physics , optics , engineering
Age‐specific incidence curves of mouse breast cancer suggest a rate‐limiting step in tumor progression one step prior to overt cancer and the withdrawal prior to middle life of a critical etiological condition (hormonal?) for one or more of the earlier steps in the oncogenic sequence.