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A cell line (SCaBER) derived from squamous cell carcinoma of the human urinary bladder
Author(s) -
O'Toole Carol,
Nayak S.,
Price Z.,
Gilbert W. H.,
Waisman J.
Publication year - 1976
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910170604
Subject(s) - karyotype , basal cell , cell culture , urinary bladder , biology , carcinoma , pathology , cell , urinary system , in vitro , chromosome , medicine , anatomy , genetics , gene
An established cell line derived from a documented squamous cell carcinoma of human urinary bladder is described. The cultured cells retained the characteristic morphology of the tumor of origin for 40 in vitro passages. Numerous desmosomes were found between cultured cells. Chromosome analysis showed hypotetraploidy with no obvious modal number, while distinctive marker chromosomes and a male karyotype were present.