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Persistence of Epstein‐barr viral nuclear antigen (EBNA) in cells entering the eb viral cycle
Author(s) -
Ernberg Ingemar,
Masucci Giuseppe,
Klein George
Publication year - 1976
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910170208
Subject(s) - antigen , virology , biology , persistence (discontinuity) , cell nucleus , virus , immunology , microbiology and biotechnology , nucleus , geotechnical engineering , engineering
It was shown by double immunofluor‐escence studies that Epstein‐Barr viral nuclear antigen (EBNA) was preserved in EBV‐infected cells after they had entered the productive viral cycle, as signalled by the appearance of the early antigen (EA) complex. A nuclear component of the EA complex could be clearly distinguished from EBNA with regard to antigenic specificity.