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Non‐organ‐specific and tumour‐specific antibodies in children with Wilms' tumour
Author(s) -
Kumar Shant,
Taylor Geoffrey
Publication year - 1975
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910160312
Subject(s) - wilms' tumor , wilms tumour , antibody , immunofluorescence , pathology , kidney , medicine , immunology
Sera from groups of children with Wilms' tumour, with non‐renal solid tumours, and from control children were studied by immunofluorescence and by absorption techniques. A high proportion of sera from both tumour groups contained non‐organ‐specific auto‐antibodies. Three of the 45 sera in the Wilms' group and one of the 27 sera in the “other” solid tumour group contained antibody reacting with normal kidney cells. Only one of 45 sera in the Wilms' tumour group contained tumour‐specific antibody.