Early appearance of a lymphoid arming factor and cytotoxic lymph‐node cells after tumor induction | Zendy

Pollack Sylvia | Zendy; Nelson Karen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Early appearance of a lymphoid arming factor and cytotoxic lymph‐node cells after tumor induction

Author(s) -

Pollack Sylvia,

Nelson Karen

Publication year - 1974

Publication title -

international journal of cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.475

H-Index - 234

eISSN - 1097-0215

pISSN - 0020-7136

DOI - 10.1002/ijc.2910140412

Subject(s) - cytotoxic t cell , lymph node , sarcoma , in vitro , pathology , lymph , lymphatic system , immunology , tumor cells , cancer research , biology , medicine , biochemistry

An arming factor which collaborates with non‐sensitized lymphoid cells to produce specific killing of tumor cells in vitro appears in the serum within 24‐48 after initiation of a tumor by inoculation of Moloney Sarcoma Virus or a transplant of syngeneic sarcoma cells. Lymph‐node cells taken 1 or 2 days after tumor induction are also specifically cytotoxic in a microcytotoxicity assay. The production of this arming factor and the appearance of cytotoxic lymphoid cells are thus temporally related and are among the early responses to syngeneic sarcomas in BALB/c mice.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research