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Antigenic relatedness of simian C‐type viruses
Author(s) -
Rangan S. R. S.
Publication year - 1974
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910130108
Subject(s) - virology , simian , antiserum , biology , virus , homologous chromosome , antigen , neutralization , leukemia , cross reactions , haplorhini , genetics , gene
The two simian C‐type viruses, gibbon lymphoma (GLV) and simian sarcoma (SSV‐1), are compared for their antigenic relatedness by serum‐neutralization techniques appropriate for the respective virus. While GLV was neutralized completely by its homologous antiserum, its replication was merely delayed by anti‐SSV‐1 serum. Both anti‐SSV‐1 and anti‐GLV antisera neutralized SSV‐1 and its associated virus (SSAV‐1). It is concluded that the simian viruses are antigenically related but distinct from each other and unrelated to feline leukemia virus. The results also suggest that SSV‐1 and SSAV‐1 possess identical envelope antigens.