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Serum alpha‐fetoprotein. VIII. Serum levels during diethylnitrosamine poisoning of baboons
Author(s) -
Purves L. R.
Publication year - 1972
Publication title -
international journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.475
H-Index - 234
eISSN - 1097-0215
pISSN - 0020-7136
DOI - 10.1002/ijc.2910100314
Subject(s) - carcinogen , toxicity , alpha (finance) , alpha fetoprotein , liver damage , medicine , physiology , endocrinology , biology , pathology , biochemistry , surgery , hepatocellular carcinoma , construct validity , patient satisfaction
Serum alpha‐fetoprotein levels rise during various stages of poisoning of baboons with diethylnitrosamine before the induction of any liver tumours. The possible mechanisms causing raised AFP levels in people from primary liver cancer high‐risk areas are discussed in the light of these experimental toxicity studies on baboons.